Анализ данных NGS

Преподаватель

• [Юрий Барбитов]

Темы занятий

• Введение общее [Intro, NGS technologies, library prep]
• QC [genomes, FASTA/FASTQ, FastQC] + short read alignment [NGS experiment types, alignment concepts, BLAST]
• Short read alignment and variant calling (logic) [SAM/BAM formats, resequencing experimens]
• Variant calling in medical genetics (overview, important routines) [alignment

statistics and visualization]

• Genome assembly [genome assembly, quality metrics]
• Assembly QC
• Metagenomics [genome annotation and genomic interval formats]
• Genome annotation
• Transcriptomics (alignment-based and alignment-free approaches)
• Transcriptomics (differential expression, clustering, GSEA)
• ChIP-Seq and other positional techniques

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Материалы

• Слайды лекций, домашние задания, дополнительные материалы